SUB1 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for SUB1 抗体 (Middle Region) (ABIN2792675)
抗原
See all SUB1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
原理
- PC4 Antibody - middle region
-
序列
- NMFQIGKMRY VSVRDFKGKV LIDIREYWMD PEGEMKPGRK GISLNPEQWS
-
交叉反应
- 牛, 犬, 小鸡, 人, 小鼠, 大鼠
-
预测反应
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 100%
-
产品特性
- This is a rabbit polyclonal antibody against PC4. It was validated on Western Blot and immunohistochemistry.
-
纯化方法
- Protein A purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PC4
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1.0 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
-
别名
- PC4
-
背景
-
Background Information: PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
Gene Name: SUB1 homolog (S. cerevisiae)
Alternative Symbols: P15, PC4, p14
Protein Name: Activated RNA polymerase II transcriptional coactivator p15
-
分子量
- 14kDa
-
基因ID
- 10923
-
NCBI登录号
- NP_006704
-
UniProt
- P53999
抗原
-