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SUB1 抗体 (AA 18-47)

SUB1 适用: 人 WB 宿主: 兔 Polyclonal RB40953 unconjugated
产品编号 ABIN1881856
发货至: 中国
  • 抗原 See all SUB1 抗体
    SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
    抗原表位
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 18-47
    适用
    • 34
    • 13
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 32
    • 2
    克隆类型
    • 33
    • 1
    多克隆
    标记
    • 23
    • 3
    • 3
    • 3
    • 1
    • 1
    This SUB1 antibody is un-conjugated
    应用范围
    • 28
    • 18
    • 15
    • 8
    • 6
    • 4
    • 2
    • 1
    Western Blotting (WB)
    预测反应
    Pr
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-47 amino acids from the Central region of human SUB1.
    克隆位点
    RB40953
    亚型
    Ig Fraction
    Top Product
    Discover our top product SUB1 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Das, Gadad, Kundu: "Human positive coactivator 4 controls heterochromatinization and silencing of neural gene expression by interacting with REST/NRSF and CoREST." in: Journal of molecular biology, Vol. 397, Issue 1, pp. 1-12, (2010) (PubMed).

    Rajagopalan, Andreeva, Teufel, Freund, Fersht: "Interaction between the transactivation domain of p53 and PC4 exemplifies acidic activation domains as single-stranded DNA mimics." in: The Journal of biological chemistry, Vol. 284, Issue 32, pp. 21728-37, (2009) (PubMed).

    Mortusewicz, Roth, Li, Cardoso, Meisterernst, Leonhardt: "Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites." in: The Journal of cell biology, Vol. 183, Issue 5, pp. 769-76, (2008) (PubMed).

    Batta, Kundu: "Activation of p53 function by human transcriptional coactivator PC4: role of protein-protein interaction, DNA bending, and posttranslational modifications." in: Molecular and cellular biology, Vol. 27, Issue 21, pp. 7603-14, (2007) (PubMed).

  • 抗原
    SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
    别名
    SUB1 (SUB1 产品)
    别名
    P15 antibody, PC4 antibody, p14 antibody, AI842364 antibody, P9 antibody, Pc4 antibody, Rpo2tc1 antibody, SUB1 homolog, transcriptional regulator antibody, SUB1 homolog (S. cerevisiae) antibody, SUB1 antibody, Sub1 antibody
    背景
    General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
    分子量
    14395
    NCBI登录号
    NP_006704
    UniProt
    P53999
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