TCF4 抗体 (N-Term)
Quick Overview for TCF4 抗体 (N-Term) (ABIN2792580)
抗原
See all TCF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- DGTPYDHMTS RDLGSHDNLS PPFVNSRIQS KTERGSYSSY GRESNLQGCH
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交叉反应
- 牛, 犬, 人, 小鼠, 大鼠
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预测反应
- Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against TCF4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TCF4
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 667 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TCF4 (Transcription Factor 4 (TCF4))
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别名
- TCF4
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背景
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TCF4 encodes transcription factor 4, a basic helix-turn-helix transcription factor. The protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. TCF4 is expressed predominantly in pre-B-cells, although it is found in other tissues as well.TCF4 encodes transcription factor 4, a basic helix-turn-helix transcription factor. The protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. TCF4 is expressed predominantly in pre-B-cells, although it is found in other tissues as well. TCF4 is known to produce multiple transcripts, however as the complete structure is only known for the transcript that encodes the b isoform, that is the variant presented here.
Alias Symbols: E2-2, ITF2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, PTHS, ITF-2, SEF-2, TCF-4, bHLHb19
Protein Interaction Partner: GOLGA8F, REXO1L6P, FAM74A4, GOLGA8EP, C9orf171, RAB41, SEC14L4, NEK8, ZDHHC24, MSRB3, FERD3L, PPP1R18, NUDT10, PATE1, TMEM213, KLC3, ZNF417, NEU4, NR2C2AP, POLR1A, SZT2, EPB41L3, MAPKBP1, SLC4A1AP, FRS3, NEK6, GLRX3, MAD2L2, BCAS2, TSSC4, CHAF1A, POLR1C,
Protein Size: 667 -
分子量
- 71 kDa
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基因ID
- 6925
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NCBI登录号
- NM_003199, NP_003190
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UniProt
- P15884
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途径
- WNT signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
抗原
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