DEK 抗体 (N-Term)
(1 reference)Quick Overview for DEK 抗体 (N-Term) (ABIN2792543)
抗原
See all DEK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AAEGEGTPTQ PASEKEPEMP GPREESEEEE DEDDEEEEEE EKEKSLIVEG
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交叉反应
- 牛, 人, 大鼠
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预测反应
- Cow: 78%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Rabbit: 85%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against DEK. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DEK
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anti-DEK Oncogene (DEK) antibody
DEK 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-DEK Oncogene (DEK) (Internal Region) antibodyDEK 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-DEK Oncogene (DEK) (AA 336-364), (C-Term) antibodyDEK 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB23679 unconjugated
anti-DEK Oncogene (DEK) (AA 343-372), (C-Term) antibodyDEK 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-DEK Oncogene (DEK) (N-Term) antibodyDEK 适用: 人, 大鼠, Cow, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-DEK Oncogene (DEK) (C-Term) antibodyDEK 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-DEK Oncogene (DEK) (Middle Region) antibodyDEK 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB Suggested Anti-DEK Antibody Titration: 1.25 µg/mL
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 375 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Down-regulation of HtrA1 activates the epithelial-mesenchymal transition and ATM DNA damage response pathways." in: PLoS ONE, Vol. 7, Issue 6, pp. e39446, (2012) (PubMed).
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: "Down-regulation of HtrA1 activates the epithelial-mesenchymal transition and ATM DNA damage response pathways." in: PLoS ONE, Vol. 7, Issue 6, pp. e39446, (2012) (PubMed).
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- DEK (DEK Oncogene (DEK))
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别名
- DEK
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背景
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DEK was first identified in a fusion with the CAN nucleoporin protein in a specific subtype of acute myelogenous leukemia. DEK has also been shown to be an autoantigen in patients with pauciarticular onset juvenile rheumatoid arthritis. Further, the last 65 amino acids of DEK can partially reverse the mutation-prone phenotype of cells from patients with ataxia-telangiectasia
Alias Symbols: D6S231E
Protein Interaction Partner: CUL3, SPOP, UBC, EED, IRF2BP2, GANAB, PTPN12, CSNK2A2, CSNK2A1, TP53BP1, ESR1, VTN, S100A9, RPL37A, DHX15, FTSJ3, WIBG, TMED9, EXOSC2, UTP14A, THRAP3, CAND1, COPS5, CDK2, YWHAZ, Cebpb, ELAVL1, SUMO1, SUMO2, RAD21, HDGF, KAT2B, EP300, CREBBP, HIST1H4A, HDA
Protein Size: 375 -
分子量
- 43 kDa
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基因ID
- 7913
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NCBI登录号
- NM_003472, NP_003463
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UniProt
- P35659
抗原
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