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DEK 抗体 (Middle Region)

DEK 适用: 人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792529
发货至: 中国
  • 抗原 See all DEK 抗体
    DEK (DEK Oncogene (DEK))
    抗原表位
    • 15
    • 10
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Middle Region
    适用
    • 47
    • 22
    • 9
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 兔, 豚鼠, 马, Pig
    宿主
    • 60
    • 2
    克隆类型
    • 52
    • 10
    多克隆
    标记
    • 23
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DEK antibody is un-conjugated
    应用范围
    • 46
    • 24
    • 22
    • 22
    • 14
    • 13
    • 13
    • 9
    • 7
    • 6
    • 3
    • 2
    • 2
    Western Blotting (WB)
    序列
    ELKETIKKLL ASANLEEVTM KQICKKVYEN YPTYDLTERK DFIKTTVKEL
    交叉反应
    牛, 小鸡, 人, 小鼠, 大鼠
    预测反应
    Cow: 85%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Pig: 78%, Rabbit: 85%, Rat: 85%
    产品特性
    This is a rabbit polyclonal antibody against DEK. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human DEK
    Top Product
    Discover our top product DEK Primary Antibody
  • 应用备注
    WB Suggested Anti-DEK Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:1562500
    Positive Control: MCF7 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 375 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Chen, Gao, Hu, Pang, Cai, Li, Wu, Jiang: "Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer." in: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 378-83, (2008) (PubMed).

  • 抗原
    DEK (DEK Oncogene (DEK))
    别名
    DEK (DEK 产品)
    别名
    D6S231E antibody, DEK antibody, 1810019E15Rik antibody, D13H6S231E antibody, DEK proto-oncogene antibody, DEK proto-oncogene L homeolog antibody, DEK oncogene (DNA binding) antibody, DEK oncogene antibody, DEK antibody, Dek antibody, dek.L antibody, LOC398543 antibody
    背景
    DEK is a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene and the presence of antibodies against this protein are all associated with various diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: D6S231E
    Protein Interaction Partner: CUL3, SPOP, UBC, EED, IRF2BP2, GANAB, PTPN12, CSNK2A2, CSNK2A1, TP53BP1, ESR1, VTN, S100A9, RPL37A, DHX15, FTSJ3, WIBG, TMED9, EXOSC2, UTP14A, THRAP3, CAND1, COPS5, CDK2, YWHAZ, Cebpb, ELAVL1, SUMO1, SUMO2, RAD21, HDGF, KAT2B, EP300, CREBBP, HIST1H4A, HDA
    Protein Size: 375
    分子量
    43 kDa
    基因ID
    7913
    NCBI登录号
    NM_003472, NP_003463
    UniProt
    P35659
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