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SMAD3 抗体 (N-Term)

This anti-SMAD3 antibody is a 兔 多克隆 antibody detecting SMAD3 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 斑马鱼, 犬 和 豚鼠.
产品编号 ABIN2792537
发货至: 中国

Quick Overview for SMAD3 抗体 (N-Term) (ABIN2792537)

抗原

See all SMAD3 抗体
SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

适用

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人, 小鼠, 大鼠, 斑马鱼, 犬, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This SMAD3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
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    N-Term

    序列

    FTPPIVKRLL GWKKGEQNGQ EEKWCEKAVK SLVKKLKKTG QLDELEKAIT

    交叉反应

    犬, 小鸡, 人, 小鼠, 猪, 大鼠

    预测反应

    Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against SMAD3. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD3
  • 应用备注

    WB Suggested Anti-SMAD3 Antibody Titration: 2.0 µg/mL
    Positive Control: Human Liver.
    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 425 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

    别名

    SMAD3

    背景

    SMAD3 is a member of Smad family proteins. SMAD family is known to be important cytoplasmic mediators of signals from the transforming growth factor-beta (TGF-beta) receptor serine/threonine kinases.
    Alias Symbols: LDS1C, MADH3, JV15-2, HSPC193, HsT17436
    Protein Interaction Partner: TEKT4, CCDC33, CPSF7, MEOX2, HDAC1, PHC2, WWP1, AES, BLZF1, UBC, TP53, SMAD4, BACH1, MAFK, FOXO3, NEDD8, TRIM33, WWP2, SMURF2, FOXM1, TRIM62, TP63, OTUB1, NEDD4L, BAG3, TGFB1I1, CSNK1D, RUNX1, HCVgp1, TSC2, FHL3, FHL2, FHL1, Melk, IRF7, RNF111, LCK, KLF5,
    Protein Size: 425

    分子量

    48 kDa

    基因ID

    4088

    NCBI登录号

    NM_005902, NP_005893

    UniProt

    Q92940

    途径

    Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
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