RAB8A 抗体 (Middle Region)
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北京 101111
Quick Overview for RAB8A 抗体 (Middle Region) (ABIN2792290)
抗原
See all RAB8A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- GIKFMETSAK ANINVENAFF TLARDIKAKM DKKLEGNSPQ GSNQGVKITP
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预测反应
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 85%, Pig: 100%, Rat: 85%, Sheep: 100%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against RAB8A. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human RAB8A
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anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibody
RAB8A 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (AA 108-207) antibodyRAB8A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (AA 68-207) antibodyRAB8A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7G8B11 unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibodyRAB8A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22933 unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (C-Term) antibodyRAB8A 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (AA 101-207) antibodyRAB8A 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibodyRAB8A 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 8A4 unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibodyRAB8A 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB7160 unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibodyRAB8A 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB4900 unconjugated Recombinant Antibody
anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibodyRAB8A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 207 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
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别名
- RAB8A
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背景
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RAB8A is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable.The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97 % , 96 %, and 51 % similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MEL, RAB8
Protein Interaction Partner: TFRC, SYTL4, SYTL1, TBC1D17, STAU1, UBC, MDM2, RPA3, RPA2, RPA1, STK4, OPTN, Myo5b, MYO5C, EHD3, EHD1, UBL4A, RAB1B, RAB31, COX5A, RAB11B, RAB7A, SCP2, RRBP1, NDUFA7, IDH3G, SNCA, ELAVL1, Rab8a, RPH3A, RAB3IP, RIMS2, RPH3AL, RABIF, MAP4K2, PDE6D, GDI2, OC
Protein Size: 207 -
分子量
- 24 kDa
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基因ID
- 4218
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NCBI登录号
- NM_005370, NP_005361
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UniProt
- P61006
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途径
- M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
抗原
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