NAPA 抗体 (N-Term)
Quick Overview for NAPA 抗体 (N-Term) (ABIN2792279)
抗原
See all NAPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MDNSGKEAEA MALLAEAERK VKNSQSFFSG LFGGSSKIEE ACEIYARAAN
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预测反应
- Cow: 100%, Dog: 100%, Mouse: 78%, Zebrafish: 78%
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产品特性
- This is a rabbit polyclonal antibody against NAPA. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NAPA
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anti-N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA) (Center) antibody
NAPA 适用: 人, 小鼠, 大鼠 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA) (AA 1-295) antibodyNAPA 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA) antibodyNAPA 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA) (AA 78-295) antibodyNAPA 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA) (AA 1-295) antibodyNAPA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA) (AA 1-295) antibody (APC)NAPA 适用: 人 IHC, ICC, IF, FACS 宿主: 兔 Polyclonal APC
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 295 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))
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别名
- NAPA
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背景
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The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37 % , 60 %, and 67 % identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively.
Alias Symbols: SNAPA
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, RNF2, ATP4A, STX5, ITGA4, FN1, VCAM1, VCP, DHX40, DHX29, THUMPD3, STAM2, VAMP2, APP, NSF, TRPC3, RTN4, STX12, GNA12, STX8, GOSR2, GOSR1, BNIP1, STX7, VAMP8, SNAP23, STX4, STX1A, SNAP25,
Protein Size: 295 -
分子量
- 33 kDa
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基因ID
- 8775
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NCBI登录号
- NM_003827, NP_003818
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UniProt
- P54920
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途径
- Synaptic Vesicle Exocytosis, Asymmetric Protein Localization
抗原
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