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CCR8 抗体 (Middle Region)

The 兔 多克隆 anti-CCR8 antibody (ABIN2792241) specifically detects CCR8 in WB. The antibody is reactive with 人, Cow 和 兔 samples.
产品编号 ABIN2792241
发货至: 中国
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Quick Overview for CCR8 抗体 (Middle Region) (ABIN2792241)

抗原

See all CCR8 抗体
CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

适用

  • 72
  • 21
  • 15
  • 1
  • 1
  • 1
  • 1
人, Cow, 兔

宿主

  • 54
  • 9
  • 6
  • 4
  • 4
  • 1
兔

克隆类型

  • 47
  • 31
多克隆

标记

  • 48
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This CCR8 antibody is un-conjugated

应用范围

  • 48
  • 33
  • 31
  • 14
  • 13
  • 12
  • 7
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 11
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    CCR8 Antibody - middle region

    序列

    MATIPLLVFY QVASEDGVLQ CYSFYNQQTL KWKIFTNFKM NILGLLIPFT

    预测反应

    Cow: 93%, Human: 100%, Rabbit: 81%

    产品特性

    This is a rabbit polyclonal antibody against CCR8. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human CCR8
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

    别名

    CCR8

    背景

    Background Information: CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. Its gene is located at the chemokine receptor gene cluster region.

    Gene Name: Chemokine (C-C motif) receptor 8

    Alternative Symbols: CY6, TER1, CCR-8, CKRL1, CDw198, CMKBR8, GPRCY6, CMKBRL2, CC-CKR-8

    Protein Name: C-C chemokine receptor type 8

    分子量

    41kDa

    基因ID

    1237

    NCBI登录号

    NP_005192

    UniProt

    P51685
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