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DOK2 抗体 (C-Term)

This anti-DOK2 antibody is a 兔 多克隆 antibody detecting DOK2 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, Pig 和 马.
产品编号 ABIN2792223
发货至: 中国

Quick Overview for DOK2 抗体 (C-Term) (ABIN2792223)

抗原

See all DOK2 抗体
DOK2

适用

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人, 小鼠, 大鼠, Cow, 犬, Pig, 马

宿主

  • 115
  • 4

克隆类型

  • 115
  • 4
多克隆

标记

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This DOK2 antibody is un-conjugated

应用范围

  • 99
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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    QEPRGEAWRR QATRDRDPAG LQHVQPAGQD FSASGWQPGT EYDNVVLKKG

    预测反应

    Cow: 100%, Dog: 90%, Horse: 90%, Human: 100%, Mouse: 90%, Pig: 100%, Rat: 90%

    产品特性

    This is a rabbit polyclonal antibody against DOK2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human DOK2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 412 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    DOK2

    别名

    DOK2

    背景

    DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. DOK2 binds p120 (RasGAP) from CML cells.The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.
    Alias Symbols: p56DOK, p56dok-2
    Protein Interaction Partner: UBC, RASA1, ABL1, POT1, EGFR, KIAA1279, INPP5D, NCK1, TEK, SRC, LYN, RET, LCK, IL4R, HCK, HSPA4L, ASF1B, DNAJB11, RAB10, SSSCA1, CFLAR, SPOP, SHC1, PSMD10, DOK1,
    Protein Size: 412

    分子量

    45 kDa

    基因ID

    9046

    NCBI登录号

    NM_003974, NP_003965

    UniProt

    O60496
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