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Caveolin 2 抗体 (N-Term)

This anti-Caveolin 2 antibody is a 兔 多克隆 antibody detecting Caveolin 2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 绵羊 和 马. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2792220
发货至: 中国

Quick Overview for Caveolin 2 抗体 (N-Term) (ABIN2792220)

抗原

See all Caveolin 2 (CAV2) 抗体
Caveolin 2 (CAV2)

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 绵羊, 马

宿主

  • 78
  • 9
  • 2
  • 1

克隆类型

  • 71
  • 19
多克隆

标记

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This Caveolin 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    序列

    LVIPYNEKPE KPAKTQKTSL DEALQWRDSL DKLLQNNYGL ASFKSFLKSE

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against CAV2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CAV2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 162 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Chi Sabins, Taylor, Fabian, Appleman, Maranchie, Stolz, Storkus: "DLK1: a novel target for immunotherapeutic remodeling of the tumor blood vasculature." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 21, Issue 10, pp. 1958-68, (2013) (PubMed).

  • 抗原

    Caveolin 2 (CAV2)

    别名

    CAV2

    背景

    CAV2 is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript.
    Alias Symbols: CAV, MGC12294
    Protein Interaction Partner: EGFR, PTGS1, CSNK2A1, CAV1, MALL, KCNMA1, UBC, DNAJA1, GOLGB1, NCK1, SRC, RASA1, FLOT2, DRD1, PLD2,
    Protein Size: 162

    分子量

    18 kDa

    基因ID

    858

    NCBI登录号

    NM_001233, NP_001224

    UniProt

    P51636

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development
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