FFAR1 抗体 (N-Term)
Quick Overview for FFAR1 抗体 (N-Term) (ABIN2792205)
抗原
See all FFAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- KVSEAALSLL VLILIITSAS RSQPKVPEWV NTPSTCCLKY YEKVLPRRLV
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预测反应
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 85%, Pig: 92%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against FFAR1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FFAR1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 300 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Identification of residues important for agonist recognition and activation in GPR40." in: The Journal of biological chemistry, Vol. 282, Issue 40, pp. 29248-55, (2007) (PubMed).
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Identification of residues important for agonist recognition and activation in GPR40." in: The Journal of biological chemistry, Vol. 282, Issue 40, pp. 29248-55, (2007) (PubMed).
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- FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
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别名
- FFAR1
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背景
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FFAR1 is receptor for medium and long chain saturated and unsaturated fatty acids. It binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C.
Alias Symbols: FFA1R, GPCR40, GPR40
Protein Interaction Partner: GNAQ, GNAI1,
Protein Size: 300 -
分子量
- 31 kDa
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基因ID
- 2864
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NCBI登录号
- NM_005303, NP_005294
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UniProt
- O14842
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
抗原
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