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CDK8 抗体 (C-Term)

CDK8 适用: 人, 小鼠, 斑马鱼, 犬, 马, 兔, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792177
发货至: 中国
  • 抗原 See all CDK8 抗体
    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
    抗原表位
    • 9
    • 8
    • 8
    • 7
    • 7
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    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    C-Term
    适用
    • 76
    • 38
    • 28
    • 6
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    • 4
    • 4
    • 4
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    • 2
    • 1
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    人, 小鼠, 斑马鱼, 犬, 马, 兔, Cow, Pig
    宿主
    • 72
    • 3
    • 1
    克隆类型
    • 64
    • 12
    多克隆
    标记
    • 40
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    This CDK8 antibody is un-conjugated
    应用范围
    • 62
    • 29
    • 11
    • 10
    • 9
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
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    Western Blotting (WB)
    序列
    GLIMTSDYQR SNPHAAYPNP GPSTSQPQSS MGYSATSQQP PQYSHQTHRY
    预测反应
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against CDK8. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human CDK8
    Top Product
    Discover our top product CDK8 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 464 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
    别名
    CDK8 (CDK8 产品)
    别名
    K35 antibody, wu:fk95h11 antibody, cyclin dependent kinase 8 antibody, cyclin-dependent kinase 8 antibody, cyclin-dependent kinase 8 S homeolog antibody, Cyclin-dependent kinase 8 antibody, cyclin dependent kinase 19 antibody, CDK8 antibody, Cdk8 antibody, cdk8 antibody, cdk8.S antibody, cdk-8 antibody, CDK19 antibody
    背景
    The protein encoded by CDK8 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.
    Alias Symbols: K35
    Protein Interaction Partner: CCNC, MED18, MED15, MED31, MED4, MED13L, MED16, MED6, MED13, MED12, MED24, MED20, MED7, MED27, MED17, MED23, MED21, MED14, HERC2, MED22, MED1, MED11, MED8, MED30, MED10, MED28, MED29, MED9, HNRNPF, CDK8, ERCC3, CCNH, MED19, TCEA1, MBP, CTD, MED26, POLR2A,
    Protein Size: 464
    分子量
    53 kDa
    基因ID
    1024
    NCBI登录号
    NM_001260, NP_001251
    UniProt
    P49336
    途径
    Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
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