CDK8 抗体 (C-Term)
Quick Overview for CDK8 抗体 (C-Term) (ABIN2792177)
抗原
See all CDK8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- GLIMTSDYQR SNPHAAYPNP GPSTSQPQSS MGYSATSQQP PQYSHQTHRY
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against CDK8. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CDK8
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anti-Cyclin-Dependent Kinase 8 (CDK8) (AA 375-464) antibody
CDK8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6H5 unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (AA 365-464) antibodyCDK8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (C-Term) antibodyCDK8 适用: 人, 小鼠 WB, ChIP-seq, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (N-Term) antibodyCDK8 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (N-Term) antibodyCDK8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (AA 21-392) antibodyCDK8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (AA 424-458), (C-Term) antibodyCDK8 适用: 人 WB 宿主: 兔 Polyclonal RB51053 unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (N-Term) antibodyCDK8 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (C-Term) antibodyCDK8 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 马, 兔, Cow, 小鸡, 非洲爪蟾, Pig, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 464 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
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别名
- CDK8
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背景
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The protein encoded by CDK8 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.
Alias Symbols: K35
Protein Interaction Partner: CCNC, MED18, MED15, MED31, MED4, MED13L, MED16, MED6, MED13, MED12, MED24, MED20, MED7, MED27, MED17, MED23, MED21, MED14, HERC2, MED22, MED1, MED11, MED8, MED30, MED10, MED28, MED29, MED9, HNRNPF, CDK8, ERCC3, CCNH, MED19, TCEA1, MBP, CTD, MED26, POLR2A,
Protein Size: 464 -
分子量
- 53 kDa
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基因ID
- 1024
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NCBI登录号
- NM_001260, NP_001251
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UniProt
- P49336
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途径
- Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
抗原
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