14-3-3 theta 抗体 (N-Term)
Quick Overview for 14-3-3 theta 抗体 (N-Term) (ABIN2792144)
抗原
See all 14-3-3 theta (YWHAQ) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SVAYKNVVGG RRSAWRVISS IEQKTDTSDK KLQLIKDYRE KVESELRSIC
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 75%
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产品特性
- This is a rabbit polyclonal antibody against YWHAQ. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human YWHAQ
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 245 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 14-3-3 theta (YWHAQ)
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别名
- YWHAQ
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背景
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YWHAQ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Alias Symbols: 1C5, HS1, 14-3-3
Protein Interaction Partner: UBC, TNFAIP3, TRIM42, RAF1, PIK3R2, PIK3C3, FUS, DTL, MAPT, ABL1, SGK1, SIK3, SUMO2, TUBGCP3, IRS4, HDAC5, HDAC4, STAU1, MDM2, TGM2, SMS, ALDH7A1, YWHAZ, YWHAH, GNAI3, G6PD, EIF5, EEF2, ECHS1, CAPNS1, CAPN1, LDHB, YWHAG, YWHAB, VCL, UBE2V1, TXNDC5, SMEK2,
Protein Size: 245 -
分子量
- 28 kDa
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基因ID
- 10971
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NCBI登录号
- NM_006826, NP_006817
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UniProt
- P27348
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途径
- Apoptosis, Myometrial Relaxation and Contraction
抗原
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