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AIF 抗体 (Middle Region)

This 兔多克隆 antibody specifically detects AIF in WB. It exhibits reactivity toward 人, 大鼠, 小鼠, Pig, Cow, 犬, 马和兔.

WB Suggested Anti-AIFM1 Antibody Titration: 1 ug/mlPositive Control: Rat tissue (AIF 抗体 (Middle Region))

3 images

产品编号 ABIN2792122

发货至: 中国

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Quick Overview for AIF 抗体 (Middle Region) (ABIN2792122)

抗原

See all AIF (AIFM1) 抗体

AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

适用

人, 大鼠, 小鼠, Pig, Cow, 犬, 马, 兔

宿主

兔

克隆类型

多克隆

标记

This AIF antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product AIFM1 Primary Antibody

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Middle Region

序列

VIFYLRDKVV VGIVLWNIFN RMPIARKIIK DGEQHEDLNE VAKLFNIHED

预测反应

Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against AIFM1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human AIFM1
anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 131-230) antibody
AIFM1 适用: 人, 大鼠, 小鼠, Pig WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) antibody
AIFM1 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E7 unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 103-322) antibody
AIFM1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (C-Term) antibody
Verified AIFM1 适用: 人, 大鼠, 小鼠, Pig WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 334-613) antibody
AIFM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) antibody
KD Validated AIFM1 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 25GB2810 unconjugated Recombinant Antibody

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 582-613), (C-Term) antibody
AIFM1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 183-195) antibody
Verified AIFM1 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 70-98), (N-Term) antibody
AIFM1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB22966 unconjugated

anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 582-613), (C-Term) antibody
AIFM1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal 2I5 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 613 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

别名

AIFM1

背景

AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene.This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Three alternative transcripts encoding different isoforms have been identified for this gene.
Alias Symbols: AIF, MGC111425, PDCD8, COXPD6
Protein Interaction Partner: ISG15, STAU1, BAG6, UBC, NEDD8, MDM2, ASB12, RNF2, BMI1, SUZ12, PARK2, BAG3, ADRB2, HDAC11, OXSR1, ILK, PAN2, NOS2, MLH1, CFTR, ESR1, TST, FSCN1, CPOX, SHC1, FBXO6, TSC22D4, CAND1, COPS5, CUL1, CUL2, CUL3, CUL5, TONSL, BLNK, PIDD1, XIAP, AMFR, Tubb4b, Tub
Protein Size: 613

分子量

67 kDa

基因ID

9131

NCBI登录号

NM_004208, NP_004199

UniProt

O95831

途径

Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect