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FLIP 抗体 (Middle Region)

CFLAR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792120
发货至: 中国
  • 抗原 See all FLIP (CFLAR) 抗体
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    抗原表位
    • 16
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    Middle Region
    适用
    • 96
    • 67
    • 57
    • 2
    • 1
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    宿主
    • 86
    • 15
    • 2
    克隆类型
    • 88
    • 15
    多克隆
    标记
    • 55
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    This FLIP antibody is un-conjugated
    应用范围
    • 98
    • 39
    • 27
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    • 21
    • 20
    • 14
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    Western Blotting (WB)
    序列
    LNPEGGKSGK APRRRAASMD SSSKLLRGRS KAPKKKPSVL PAPPEGATPT
    预测反应
    Human: 100%
    产品特性
    This is a rabbit polyclonal antibody against CFLAR. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human CFLAR
    Top Product
    Discover our top product CFLAR Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 480 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    别名
    CFLAR (CFLAR 产品)
    别名
    Clarp1 antibody, cflar antibody, CFLAR antibody, FLIP antibody, CASH antibody, CASP8AP1 antibody, CLARP antibody, Casper antibody, FLAME antibody, FLAME-1 antibody, FLAME1 antibody, I-FLICE antibody, MRIT antibody, c-FLIP antibody, c-FLIPL antibody, c-FLIPR antibody, c-FLIPS antibody, 2310024N18Rik antibody, A430105C05Rik antibody, Cash antibody, ENSMUSG00000072980 antibody, Flip antibody, Gm9845 antibody, c-Flip antibody, CASP8 and FADD-like apoptosis regulator a antibody, CASP8 and FADD like apoptosis regulator antibody, CASP8 and FADD like apoptosis regulator S homeolog antibody, CASP8 and FADD-like apoptosis regulator antibody, cflara antibody, CFLAR antibody, cflar antibody, cflar.S antibody, Cflar antibody
    背景
    CFLAR belongs to the peptidase C14A family. It is a apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. The protein acts as an inhibitor of TNFRSF6 mediated apoptosis. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. CFLAR lacks enzymatic (caspase) activity.
    Alias Symbols: CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLIP, I-FLICE, MRIT, USURPIN, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, FLAME1
    Protein Interaction Partner: FADD, TRAF1, GSN, SPATS1, TNFSF10, RIPK1, RAF1, SMAD3, CASP8, HSP90AA1, STUB1, TNFRSF10A, TNFRSF10B, UBC, FASLG, ITCH, DAXX, CBLB, ATG3, XRCC6, Mib1, TP53, DEDD2, DEDD, RIPK2, IKBKB, MAP2K7, TRAF2, CASP10, CASP7, CASP6, MAP2K4, PSEN2, CASP2, CASP3, BCL2L1
    Protein Size: 480
    分子量
    55 kDa
    基因ID
    8837
    NCBI登录号
    NM_003879, NP_003870
    UniProt
    O15519
    途径
    Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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