Exportin 2 抗体 (N-Term)
Quick Overview for Exportin 2 抗体 (N-Term) (ABIN2792099)
抗原
See all Exportin 2 (CSE1L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ELSDANLQTL TEYLKKTLDP DPAIRRPAEK FLESVEGNQN YPLLLLTLLE
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against CSE1L. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CSE1L
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anti-CSE1 Chromosome Segregation 1-Like (CSE1L) (AA 872-971) antibody
CSE1L 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3D8 unconjugated
anti-CSE1 Chromosome Segregation 1-Like (CSE1L) (Center) antibodyCSE1L 适用: 人, 小鼠, 大鼠 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-CSE1 Chromosome Segregation 1-Like (CSE1L) (AA 713-971) antibodyCSE1L 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-CSE1 Chromosome Segregation 1-Like (CSE1L) (AA 872-972) antibodyCSE1L 适用: 人 WB, ELISA, IF, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-CSE1 Chromosome Segregation 1-Like (CSE1L) (AA 872-972) antibodyCSE1L 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3D8 unconjugated
anti-CSE1 Chromosome Segregation 1-Like (CSE1L) (AA 901-971) antibodyCSE1L 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CSE1 Chromosome Segregation 1-Like (CSE1L) (N-Term) antibodyCSE1L 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 犬 WB, IF, IHC, IP, IC 宿主: 兔 Polyclonal unconjugated
anti-CSE1 Chromosome Segregation 1-Like (CSE1L) (AA 1-50) antibodyCSE1L 适用: 人 WB, ELISA, IF, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-CSE1 Chromosome Segregation 1-Like (CSE1L) (N-Term) antibodyCSE1L 适用: 人 WB, ELISA, IF, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-CSE1 Chromosome Segregation 1-Like (CSE1L) (N-Term) antibodyCSE1L 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 犬, 兔, 马, Pig, 斑马鱼, 豚鼠, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 971 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))
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别名
- CSE1L
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背景
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Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the protein may play a role both in apoptosis and in cell proliferation.Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CAS, CSE1, MGC117283, MGC130036, MGC130037, XPO2
Protein Interaction Partner: ERLIN2, HUWE1, UBC, FUS, SUMO2, STAU1, SUMO1, NEDD8, ASB16, RNF2, SUZ12, PDIA3, TBCB, CKB, GINS3, BCCIP, UBFD1, CNDP2, SCLY, CHORDC1, RRAGB, GDA, NPEPPS, SLC9A3R1, KYNU, TGM2, TCEA1, SMS, RPS6KA3, MVD, LDHA, FBXO6, YWHAQ, EGFR, UBD, PTMA, CLN3, HDAC6, MMS
Protein Size: 971 -
分子量
- 110 kDa
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基因ID
- 1434
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NCBI登录号
- NM_001316, NP_001307
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UniProt
- P55060
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途径
- Protein targeting to Nucleus
抗原
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