FLIP 抗体 (N-Term)
Quick Overview for FLIP 抗体 (N-Term) (ABIN2792098)
抗原
See all FLIP (CFLAR) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- HQVEEALDTD EKEMLLFLCR DVAIDVVPPN VRDLLDILRE RGKLSVGDLA
-
预测反应
- Cow: 100%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 80%, Rat: 80%
-
产品特性
- This is a rabbit polyclonal antibody against CFLAR. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Protein A purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CFLAR
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 480 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
-
别名
- CFLAR
-
背景
-
CFLAR might contribute to the carcinogenesis and aggressiveness of endometrial carcinoma and might be a useful prognostic factor in the tumor. CFLAR is specially overexpressed in colon cancers and it might contribute to carcinogenesis of normal colonic mucosa.
Alias Symbols: CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1
Protein Interaction Partner: FADD, TRAF1, GSN, SPATS1, TNFSF10, RIPK1, RAF1, SMAD3, CASP8, HSP90AA1, STUB1, TNFRSF10A, TNFRSF10B, UBC, FASLG, ITCH, DAXX, CBLB, ATG3, XRCC6, Mib1, TP53, DEDD2, DEDD, RIPK2, IKBKB, MAP2K7, TRAF2, CASP10, CASP7, CASP6, MAP2K4, PSEN2, CASP2, CASP3, BCL2L1
Protein Size: 480 -
分子量
- 55 kDa
-
基因ID
- 8837
-
NCBI登录号
- NM_003879, NP_003870
-
UniProt
- O15519
-
途径
- Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
-