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NME1 抗体 (N-Term)

This anti-NME1 antibody is a 兔 多克隆 antibody detecting NME1 in WB, IHC 和 DB. Suitable for 人, 小鼠, 大鼠, Cow, 马, 兔 和 豚鼠.
产品编号 ABIN2792090
发货至: 中国

Quick Overview for NME1 抗体 (N-Term) (ABIN2792090)

抗原

See all NME1 抗体
NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

适用

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人, 小鼠, 大鼠, Cow, 马, 兔, 豚鼠

宿主

  • 86
  • 30
  • 2
  • 1

克隆类型

  • 84
  • 34
多克隆

标记

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This NME1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Dot Blot (DB)
  • 抗原表位

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    N-Term

    序列

    ANCERTFIAI KPDGVQRGLV GEIIKRFEQK GFRLVGLKFM QASEDLLKEH

    预测反应

    Cow: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against NME1. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human NME1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 152 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

    别名

    NME1

    背景

    This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
    Alias Symbols: AWD, GAAD, NDPKA, NM23, NM23-H1, NB, NBS, NDKA, NDPK-A
    Protein Interaction Partner: SREK1IP1, PID1, TNPO2, POLR1C, NME4, NME3, NME1, TUBG1, UBC, MDM2, ASB18, BMI1, CHRAC1, NME1-NME2, WDR1, THOP1, SORD, RBBP7, OXCT1, IDH1, FDPS, MAPK14, FBXO6, WDYHV1, NIF3L1, SOX30, FXR2, SMARCD1, NME2, CCND3, UROD, SOD1, MIF, ERG, EBNA-LP, HDAC5, STRAP,
    Protein Size: 152

    分子量

    17 kDa

    基因ID

    4830

    NCBI登录号

    NM_000269, NP_000260

    UniProt

    P22392

    途径

    Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
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