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FANCD2 抗体 (Middle Region)

FANCD2 适用: 人, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2792058
发货至: 中国
  • 抗原 See all FANCD2 抗体
    FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
    抗原表位
    • 16
    • 15
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    • 8
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    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    Middle Region
    适用
    • 101
    • 25
    • 22
    • 1
    人, 马, Pig
    宿主
    • 100
    • 2
    克隆类型
    • 90
    • 12
    多克隆
    标记
    • 34
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This FANCD2 antibody is un-conjugated
    应用范围
    • 28
    • 27
    • 27
    • 24
    • 16
    • 14
    • 12
    • 9
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    TPHTVTAISA KIRKKGKIER KQKTDGSKTS SSDTLSEEKN SECDPTPSHR
    预测反应
    Horse: 79%, Human: 100%, Pig: 79%
    产品特性
    This is a rabbit polyclonal antibody against FANCD2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human FANCD2
    Top Product
    Discover our top product FANCD2 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
    别名
    FANCD2 (FANCD2 产品)
    别名
    FANCD2 antibody, CG17269 antibody, CG31192 antibody, CG31194 antibody, Dmel\\CG17269 antibody, dmFANCD2 antibody, xfancd2 antibody, FA-D2 antibody, FA4 antibody, FACD antibody, FAD antibody, FAD2 antibody, FANCD antibody, 2410150O07Rik antibody, AU015151 antibody, BB137857 antibody, Fanconi anemia complementation group D2 antibody, CG17269 gene product from transcript CG17269-RA antibody, Fanconi anemia group D2 protein antibody, Fanconi anemia, complementation group D2 antibody, Fanconi anemia complementation group D2 L homeolog antibody, FANCD2 antibody, Fancd2 antibody, LOC100455970 antibody, fancd2 antibody, fancd2.L antibody
    背景
    The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants.
    Alias Symbols: FA4, FAD, FACD, FAD2, FA-D2, FANCD
    Protein Size: 749
    分子量
    82 kDa
    基因ID
    2177
    NCBI登录号
    NM_001018115, NP_001018125
    UniProt
    Q9BXW9
    途径
    DNA Damage Repair
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