MACROD1 抗体 (N-Term)
This anti-MACROD1 antibody is a 兔 多克隆 antibody detecting MACROD1 in WB. Suitable for 人, Cow, 犬, 豚鼠, 马, 小鼠 和 大鼠.
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Quick Overview for MACROD1 抗体 (N-Term) (ABIN2791083)
抗原
MACROD1
(MACRO Domain Containing 1 (MACROD1))
适用
人, Cow, 犬, 豚鼠, 马, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This MACROD1 antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- N-Term
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序列
- MAAKVDLSTS TDWKEAKSFL KGLSDKQREE HYFCKDFVRL KKIPTWKEMA
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预测反应
- Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against MACROD1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human MACROD1
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anti-MACRO Domain Containing 1 (MACROD1) (AA 83-325) antibody
MACROD1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MACRO Domain Containing 1 (MACROD1) (AA 83-132) antibodyMACROD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 325 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MACROD1 (MACRO Domain Containing 1 (MACROD1))
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别名
- MACROD1
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背景
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MACROD1 deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. It plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen and may play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. It could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction and could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. MACROD1 enhances ESR1-mediated transcription activity.
Alias Symbols: LRP16
Protein Interaction Partner: BAG3, EPB41,
Protein Size: 325 -
分子量
- 36 kDa
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基因ID
- 28992
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NCBI登录号
- NM_014067, NP_054786
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UniProt
- Q9BQ69
抗原
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