MYSM1 抗体 (C-Term)
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北京 101111
Quick Overview for MYSM1 抗体 (C-Term) (ABIN2790657)
抗原
See all MYSM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- MYSM1 Antibody - C-terminal region
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序列
- CLQKLLECMR KTLSKVTNCF MAEEFLTEIE NLFLSNYKSN QENGVTEENC
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预测反应
- Dog: 86%, Human: 100%, Rabbit: 77%
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产品特性
- This is a rabbit polyclonal antibody against MYSM1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human MYSM1
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anti-Myb-Like, SWIRM and MPN Domains 1 (MYSM1) (Internal Region) antibody
MYSM1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myb-Like, SWIRM and MPN Domains 1 (MYSM1) antibodyMYSM1 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myb-Like, SWIRM and MPN Domains 1 (MYSM1) (AA 118-147), (N-Term) antibodyMYSM1 适用: 人, 小鼠 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Myb-Like, SWIRM and MPN Domains 1 (MYSM1) (AA 111-139), (N-Term) antibodyMYSM1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB27661 unconjugated
anti-Myb-Like, SWIRM and MPN Domains 1 (MYSM1) (AA 170-311) antibodyMYSM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myb-Like, SWIRM and MPN Domains 1 (MYSM1) (AA 145-194) antibodyMYSM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67188-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
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别名
- MYSM1
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背景
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Background Information: MYSM1 is a metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. It preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. MYSM1 acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
Alternative Symbols: 2ADUB, BMFS4, 2A-DUB
Protein Name: Histone H2A deubiquitinase MYSM1
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分子量
- 91kDa
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基因ID
- 114803
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NCBI登录号
- NP_001078956
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UniProt
- Q5VVJ2
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途径
- Chromatin Binding
抗原
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