MYSM1 抗体 (AA 490-570)
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北京 101111
Quick Overview for MYSM1 抗体 (AA 490-570) (ABIN7215936)
抗原
See all MYSM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 490-570
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原理
- Rabbit Anti-MYSM1 Polyclonal Antibody
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特异性
- MYSM1 Polyclonal Antibody detects endogenous levels of MYSM1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human MYSM1 at AA range: 490-570
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亚型
- IgG
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anti-Myb-Like, SWIRM and MPN Domains 1 (MYSM1) antibody
MYSM1 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myb-Like, SWIRM and MPN Domains 1 (MYSM1) (AA 118-147), (N-Term) antibodyMYSM1 适用: 人, 小鼠 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Myb-Like, SWIRM and MPN Domains 1 (MYSM1) (AA 111-139), (N-Term) antibodyMYSM1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB27661 unconjugated
anti-Myb-Like, SWIRM and MPN Domains 1 (MYSM1) (Internal Region) antibodyMYSM1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myb-Like, SWIRM and MPN Domains 1 (MYSM1) (AA 170-311) antibodyMYSM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myb-Like, SWIRM and MPN Domains 1 (MYSM1) (AA 145-194) antibodyMYSM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
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别名
- MYSM1
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背景
- MYSM1, KIAA1915, Histone H2A deubiquitinase MYSM1, 2A-DUB, Myb-like, SWIRM and MPN domain-containing protein 1MYSM1 (Myb Like, SWIRM And MPN Domains 1) is a Protein Coding gene. Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Diseases associated with MYSM1 include hemorrhagic cystitis. Gene Ontology (GO) annotations related to this gene include chromatin binding and protein complex binding. An important paralog of this gene is MPND.
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分子量
- 95kD
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基因ID
- 114803
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UniProt
- Q5VVJ2
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途径
- Chromatin Binding
抗原
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