RIN2 抗体 (N-Term)
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Quick Overview for RIN2 抗体 (N-Term) (ABIN2790373)
抗原
See all RIN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RTDVNLENGL EPAETHSMVR HKDGGYSEEE DVKTCARDSG YDSLSNRLSI
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预测反应
- Cow: 80%, Dog: 80%, Horse: 80%, Human: 100%, Mouse: 83%, Pig: 80%, Rat: 83%
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产品特性
- This is a rabbit polyclonal antibody against RIN2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of human RIN2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RIN2 (Ras and Rab Interactor 2 (RIN2))
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别名
- RIN2
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背景
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The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.
Alias Symbols: MACS, RASSF4
Protein Size: 462 -
分子量
- 50 kDa
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基因ID
- 54453
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NCBI登录号
- NM_001242581, NP_001229510
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UniProt
- Q8WYP3
抗原
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