CHMP5 抗体 (C-Term)
Quick Overview for CHMP5 抗体 (C-Term) (ABIN2790285)
抗原
See all CHMP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LDALGDELLA DEDSSYLDEA ASAPAIPEGV PTDTKNKDGV LVDEFGLPQI
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 80%
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产品特性
- This is a rabbit polyclonal antibody against Chmp5. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Chmp5
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anti-Charged Multivesicular Body Protein 5 (CHMP5) antibody
CHMP5 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 5 (CHMP5) (AA 1-219) antibodyCHMP5 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 5 (CHMP5) (C-Term) antibodyVerified CHMP5 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 219 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))
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别名
- Chmp5
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背景
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Chmp5 is a probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis. ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.
Alias Symbols: 2210412K09Rik, AW545668
Protein Interaction Partner: Ndn,
Protein Size: 219 -
分子量
- 24 kDa
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基因ID
- 76959
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NCBI登录号
- NM_029814, NP_084090
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UniProt
- Q9D7S9
抗原
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