DCLK1 抗体 (C-Term)
Quick Overview for DCLK1 抗体 (C-Term) (ABIN2789984)
抗原
See all DCLK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- IFIACGPEKF RYQDDFLLDE SECRVVKSTS YTKIASSSRR STTKSPGPSR
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against DCLK1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of human DCLK1
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anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 390-647) antibody
DCLK1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 640-729) antibodyDCLK1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6H4 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 690-720) antibodyDCLK1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB3161 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 143-381) antibodyDCLK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 390-647) antibodyDCLK1 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) antibodyDCLK1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 1-30), (N-Term) antibodyDCLK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB3059 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) antibodyDCLK1 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 1751CT665-1-72 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 640-729) antibodyDCLK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 640-729) antibodyDCLK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6F9 unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
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别名
- DCLK1
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背景
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This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.
Alias Symbols: CL1, DCLK, CLICK1, DCDC3A, DCAMKL1
Protein Size: 363 -
分子量
- 39 kDa
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基因ID
- 9201
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NCBI登录号
- NM_001195415, NP_001182344
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UniProt
- O15075
抗原
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