IDO1 抗体 (C-Term)
Quick Overview for IDO1 抗体 (C-Term) (ABIN2789915)
抗原
See all IDO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- ILIPASQQPK ENKTSEDPSK LEAKGTGGTD LMNFLKTVRS TTEKSLLKEG
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预测反应
- Human: 100%, Pig: 79%, Rabbit: 93%
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产品特性
- This is a rabbit polyclonal antibody against IDO1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 403 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
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别名
- IDO1
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背景
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This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
Alias Symbols: IDO, INDO, IDO-1
Protein Interaction Partner: UBC, APP, TERF2IP, PPP1R16A, DDX24,
Protein Size: 403 -
分子量
- 45 kDa
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基因ID
- 3620
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NCBI登录号
- NM_002164, NP_002155
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UniProt
- P14902
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途径
- Activated T Cell Proliferation
抗原
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