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Sortilin 1 抗体 (C-Term)

SORT1 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789904
发货至: 中国
  • 抗原 See all Sortilin 1 (SORT1) 抗体
    Sortilin 1 (SORT1)
    抗原表位
    • 16
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔
    宿主
    • 42
    • 5
    • 2
    克隆类型
    • 44
    • 5
    多克隆
    标记
    • 25
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Sortilin 1 antibody is un-conjugated
    应用范围
    • 38
    • 19
    • 17
    • 13
    • 13
    • 12
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    YVCGGRFLVH RYSVLQQHAE ANGVDGVDAL DTASHTNKSG YHDDSDEDLL
    预测反应
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against SORT1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product SORT1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 831 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Sortilin 1 (SORT1)
    别名
    SORT1 (SORT1 产品)
    别名
    SORT1 antibody, 19.m02079 antibody, gp95 antibody, ldlcq6 antibody, sortilin antibody, Gp95 antibody, LDLCQ6 antibody, NT3 antibody, 2900053A11Rik antibody, AI852375 antibody, Ntr3 antibody, Ntsr3 antibody, Nt3 antibody, Nts3 antibody, sort1 antibody, zgc:85953 antibody, sortilin 1 antibody, sortilin antibody, sortilin 1 S homeolog antibody, sortilin 1a antibody, SORT1 antibody, TP01_0016 antibody, BBOV_I002730 antibody, sort1.S antibody, Sort1 antibody, sort1a antibody
    背景
    This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes, however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p, the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins.
    Alias Symbols: Gp95, NT3
    Protein Interaction Partner: NUDCD3, UBC, SORCS1, GGA1, GGA3, GGA2, STAM, ELAVL1, NTS, NGF, NGFR, BDNF, LRPAP1, CDK2, SLC2A4,
    Protein Size: 831
    分子量
    84 kDa
    基因ID
    6272
    NCBI登录号
    NM_002959, NP_002950
    UniProt
    Q99523
    途径
    Neurotrophin Signaling Pathway
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