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Sortilin 1 抗体 (C-Term)

SORT1 适用: 人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789904
发货至: 中国
  • 抗原 See all Sortilin 1 (SORT1) 抗体
    Sortilin 1 (SORT1)
    抗原表位
    • 16
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 大鼠, 小鼠, 犬, Cow, 豚鼠, 马, 兔
    宿主
    • 47
    • 5
    • 2
    克隆类型
    • 49
    • 5
    多克隆
    标记
    • 24
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Sortilin 1 antibody is un-conjugated
    应用范围
    • 37
    • 19
    • 17
    • 13
    • 13
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    YVCGGRFLVH RYSVLQQHAE ANGVDGVDAL DTASHTNKSG YHDDSDEDLL
    预测反应
    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against SORT1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product SORT1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 831 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Sortilin 1 (SORT1)
    别名
    SORT1 (SORT1 产品)
    背景
    This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes, however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p, the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins.
    Alias Symbols: Gp95, NT3
    Protein Interaction Partner: NUDCD3, UBC, SORCS1, GGA1, GGA3, GGA2, STAM, ELAVL1, NTS, NGF, NGFR, BDNF, LRPAP1, CDK2, SLC2A4,
    Protein Size: 831
    分子量
    84 kDa
    基因ID
    6272
    NCBI登录号
    NM_002959, NP_002950
    UniProt
    Q99523
    途径
    Neurotrophin Signaling Pathway
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