Sortilin 1 抗体 (C-Term)
Quick Overview for Sortilin 1 抗体 (C-Term) (ABIN2789904)
抗原
See all Sortilin 1 (SORT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- YVCGGRFLVH RYSVLQQHAE ANGVDGVDAL DTASHTNKSG YHDDSDEDLL
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against SORT1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Sortilin 1 (SORT1) (AA 203-299) antibody
SORT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Sortilin 1 (SORT1) (AA 520-760) antibodySORT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 328-457) antibodySORT1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 320-335), (Extracellular) antibodyKO Validated SORT1 适用: 人 WB, IHC, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 731-831) antibodySORT1 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 50-320) antibodySORT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 203-299) antibodySORT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) antibodyKD Validated SORT1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
anti-Sortilin 1 (SORT1) (AA 320-335), (Extracellular) antibody (FITC)SORT1 适用: 人 FACS 宿主: 兔 Polyclonal FITC
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 831 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Sortilin 1 (SORT1)
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别名
- SORT1
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背景
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This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes, however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p, the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins.
Alias Symbols: Gp95, NT3
Protein Interaction Partner: NUDCD3, UBC, SORCS1, GGA1, GGA3, GGA2, STAM, ELAVL1, NTS, NGF, NGFR, BDNF, LRPAP1, CDK2, SLC2A4,
Protein Size: 831 -
分子量
- 84 kDa
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基因ID
- 6272
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NCBI登录号
- NM_002959, NP_002950
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UniProt
- Q99523
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途径
- Neurotrophin Signaling Pathway
抗原
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