DMGDH 抗体 (Middle Region)
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Quick Overview for DMGDH 抗体 (Middle Region) (ABIN2789895)
抗原
See all DMGDH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SELHDLRWIE EAAFRGGYDV EIQNITDEFG VLGVAGPYAR RVLQKLTSE
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%
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产品特性
- This is a rabbit polyclonal antibody against Dmgdh. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of mouse DMGDH
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DMGDH (Dimethylglycine Dehydrogenase (DMGDH))
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别名
- Dmgdh
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背景
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This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
Alias Symbols: DMGDHD, ME2GLYDH
Protein Size: 869 -
分子量
- 93 kDa
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基因ID
- 29958
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NCBI登录号
- NM_013391, NP_037523
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UniProt
- Q9UI17
抗原
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