DMGDH 抗体 (AA 790-870)
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Quick Overview for DMGDH 抗体 (AA 790-870) (ABIN7214582)
抗原
See all DMGDH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 790-870
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原理
- Rabbit Anti-DMGDH Polyclonal Antibody
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特异性
- DMGDH Polyclonal Antibody detects endogenous levels of DMGDH protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the C-terminal region of human DMGDH at AA range: 790-870
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- DMGDH (Dimethylglycine Dehydrogenase (DMGDH))
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别名
- DMGDH
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背景
- DMGDH, Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDHDMGDH encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme (dimethylglycine dehydrogenase) is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.
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分子量
- 97kD
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基因ID
- 29958
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UniProt
- Q9UI17
抗原
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