GPBAR1 抗体 (C-Term)
Quick Overview for GPBAR1 抗体 (C-Term) (ABIN2789752)
抗原
See all GPBAR1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- AAAVPVAMGL GDQRYTAPWR AAAQRCLQGL WGRASRDSPG PSIAYHPSSQ
-
预测反应
- Human: 100%, Rat: 100%
-
产品特性
- This is a rabbit polyclonal antibody against GPBAR1. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 330 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
-
别名
- GPBAR1
-
背景
-
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.
Alias Symbols: BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5
Protein Size: 330 -
分子量
- 35 kDa
-
基因ID
- 151306
-
NCBI登录号
- NM_170699, NP_733800
-
UniProt
- Q8TDU6
-
途径
- WNT signaling, Hormone Transport, Sensory Perception of Sound
抗原
-