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WISP2 抗体 (C-Term)

This anti-WISP2 antibody is a 兔 多克隆 antibody detecting WISP2 in WB. Suitable for 人, 大鼠, 犬, 马 和 Pig.
产品编号 ABIN2789751
发货至: 中国

Quick Overview for WISP2 抗体 (C-Term) (ABIN2789751)

抗原

See all WISP2 抗体
WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

适用

人, 大鼠, 犬, 马, Pig

宿主

  • 42
  • 8

克隆类型

  • 43
  • 7
多克隆

标记

  • 32
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This WISP2 antibody is un-conjugated

应用范围

  • 38
  • 18
  • 18
  • 12
  • 11
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 9
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term

    序列

    WGPCSTTCGL GMATRVSNQN RFCRLETQRR LCLSRPCPPS RGRSPQNSAF

    预测反应

    Dog: 79%, Horse: 79%, Human: 100%, Pig: 79%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against WISP2. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 250 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    WISP2 (WNT1 Inducible Signaling Pathway Protein 2 (WISP2))

    别名

    WISP2

    背景

    This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72 % identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.
    Alias Symbols: CCN5, CT58, CTGF-L
    Protein Interaction Partner: HDAC3, HDAC1, IGF1R, IGF2R,
    Protein Size: 250

    分子量

    24 kDa

    基因ID

    8839

    NCBI登录号

    NM_003881, NP_003872

    UniProt

    O76076

    途径

    WNT signaling, Growth Factor Binding
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