PRKAG3 抗体 (N-Term)
Quick Overview for PRKAG3 抗体 (N-Term) (ABIN2789710)
抗原
See all PRKAG3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ENSSSWPSPA VTSSSERIRG KRRAKALRWT RQKSVEEGEP PGQGEGPRSR
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against PRKAG3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 489 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
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别名
- PRKAG3
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背景
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The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
Alias Symbols: AMPKG3
Protein Interaction Partner: BAG3, KLC1, CRYAB, NGRN, LMCD1, PRKAA1, PRKAB2, PRKAB1,
Protein Size: 489 -
分子量
- 54 kDa
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基因ID
- 53632
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NCBI登录号
- NM_017431, NP_059127
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UniProt
- Q9UGI9
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途径
- AMPK Signaling, Cellular Glucan Metabolic Process, Warburg Effect
抗原
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