LIMS1 抗体 (Middle Region)
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- 抗原 See all LIMS1 抗体
- LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, 山羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LIMS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- HLCRPCHNRE KARGLGKYIC QKCHAIIDEQ PLIFKNDPYH PDHFNCANCG
- 预测反应
- Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- 产品特性
- This is a rabbit polyclonal antibody against LIMS1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human LIMS1
- Top Product
- Discover our top product LIMS1 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 387 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
- 别名
- LIMS1 (LIMS1 产品)
- 背景
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The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PINCH, PINCH1
Protein Interaction Partner: RSU1, UBC, SUMO1, NEDD8, ILK, STUB1, MAPT, MBIP, Hoxa1, HNRNPU, STK11, PARVA, SMURF1, EHMT2, LPXN, NCK2, RBBP8, TMSB4X, TGFBR1, ACP6,
Protein Size: 387 - 分子量
- 44 kDa
- 基因ID
- 3987
- NCBI登录号
- NM_001193485, NP_001180414
- UniProt
- B7Z7R3
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