PICALM 抗体 (Middle Region)
Quick Overview for PICALM 抗体 (Middle Region) (ABIN2789681)
抗原
See all PICALM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- ALEQHLASLE GKKIKDSTAA SRATTLSNAV SSLASTGLSL TKVDEREKQA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against PICALM. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 517-624) antibody
PICALM 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 420-646) antibodyPICALM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 251-350) antibodyPICALM 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 385-415) antibodyPICALM 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB53756 unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 512-543) antibodyPICALM 适用: 人 WB 宿主: 兔 Polyclonal RB54131 unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 1-307) antibodyPICALM 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 1-610) antibodyPICALM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 438-487) antibodyPICALM 适用: 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 277-326) antibodyPICALM 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol Binding clathrin Assembly Protein (PICALM) (AA 290-460) antibodyPICALM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 652 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PICALM (Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))
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别名
- PICALM
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背景
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This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10,11)(p13,q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease.
Alias Symbols: CALM, CLTH, LAP
Protein Interaction Partner: UBC, PELI2, VCAM1, ITGA4, FN1, SIRT1, ILF3, EGFR, EEF1A1, DNM2, CD55, ABCC2, ATP6V1E1, AP2A1, SH3GLB2, FLOT1, HNRNPDL, SEC24D, SEC24C, ATP6V1F, HIP1R, LAMTOR3, ITSN1, EHD2, CASP8, CLTCL1, CASP3, PLCG1, DDIT3, CLTC,
Protein Size: 652 -
分子量
- 71 kDa
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基因ID
- 8301
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NCBI登录号
- NM_007166, NP_009097
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UniProt
- Q13492
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途径
- Synaptic Membrane
抗原
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