CD276 抗体 (C-Term)
Quick Overview for CD276 抗体 (C-Term) (ABIN2789671)
抗原
See all CD276 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - C-Term
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序列
 - VCLIALLVAL AFVCWRKIKQ SCEEENAGAE DQDGEGEGSK TALQPLKHSD
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预测反应
 - Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%
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产品特性
 - This is a rabbit polyclonal antibody against CD276. It was validated on Western Blot.
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纯化方法
 - Affinity Purified
 
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应用备注
 - Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 316 AA
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - Lot specific
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缓冲液
 - Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Avoid repeated freeze-thaw cycles.
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储存条件
 - -20 °C
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储存方法
 - For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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- CD276
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别名
 - CD276
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背景
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                        The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: B7-H3, B7H3, B7RP-2, 4Ig-B7-H3
Protein Interaction Partner: UBC, RYK,
Protein Size: 316 - 
                                            
分子量
 - 34 kDa
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基因ID
 - 80381
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NCBI登录号
 - NM_025240, NP_079516
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途径
 - Cancer Immune Checkpoints
 
抗原
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