WISP1 抗体 (Middle Region)
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北京 101111
Quick Overview for WISP1 抗体 (Middle Region) (ABIN2789653)
抗原
See all WISP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- WISP1 Antibody - middle region
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序列
- VRPPRLWCPH PRRVSIPGHC CEQWVCEDDA KRPRKTAPRD TGAFDAVGEV
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预测反应
- Cow: 92%, Human: 100%, Pig: 85%
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产品特性
- This is a rabbit polyclonal antibody against WISP1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (C-Term) antibody
Verified WISP1 适用: 人 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 213-350) antibodyWISP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (C-Term) antibodyWISP1 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 130-251) antibodyWISP1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 171-200) antibodyWISP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2115-2116 unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 1-280) antibodyWISP1 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 237-295) antibodyWISP1 适用: 人 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (C-Term) antibodyWISP1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 216-347) antibodyWISP1 适用: 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-WNT1 Inducible Signaling Pathway Protein 1 (WISP1) (AA 216-347) antibodyWISP1 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63882-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
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别名
- WISP1
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背景
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Background Information: This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase.
Gene Name: WNT1 inducible signaling pathway protein 1
Alternative Symbols: WISP1, WISP1c, WISP1i, WISP1tc, WISP1-OT1, WISP1-UT1
Protein Name: WNT1-inducible-signaling pathway protein 1
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分子量
- 38kDa
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基因ID
- 8840
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NCBI登录号
- NP_003873
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UniProt
- O95388
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途径
- WNT signaling, Growth Factor Binding
抗原
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