MASP1 抗体 (N-Term)
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Quick Overview for MASP1 抗体 (N-Term) (ABIN2789651)
抗原
See all MASP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PGSFMSITFR SDFSNEERFT GFDAHYMAVD VDECKEREDE ELSCDHYCHN
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against MASP1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human MASP1
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anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 20-447) antibody
MASP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 25-453) antibodyMASP1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 20-120) antibodyMASP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 1-380) antibodyMASP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (cleaved), (Internal Region) antibodyMASP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 20-699) antibodyMASP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 1-380) antibodyMASP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 699 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
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别名
- MASP1
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背景
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This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway.
Alias Symbols: CRARF, CRARF1, DKFZp686I01199, FLJ26383, MASP, MGC126283, MGC126284, PRSS5, RaRF
Protein Interaction Partner: CDK19, CUL3, PDCD6IP, RPS6KA6, MAPK8IP2, NUDT21, NCK2, UFD1L, RPS6KA3, MAPK6, H2AFX, GSK3B, GADD45A, C2, SERPING1, FCN2, MBL2, C3, MASP2,
Protein Size: 699 -
分子量
- 28 kDa
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基因ID
- 5648
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NCBI登录号
- NM_001879, NP_001870
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UniProt
- P48740
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途径
- Complement System
抗原
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