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PLAU 抗体 (C-Term)

PLAU 适用: 人, 兔, 马, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789605
发货至: 中国
  • 抗原 See all PLAU 抗体
    PLAU (Plasminogen Activator, Urokinase (PLAU))
    抗原表位
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 78
    • 25
    • 20
    • 3
    • 3
    • 3
    人, 兔, 马, Saccharomyces cerevisiae
    宿主
    • 73
    • 13
    • 10
    • 5
    克隆类型
    • 79
    • 19
    • 1
    多克隆
    标记
    • 60
    • 13
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PLAU antibody is un-conjugated
    应用范围
    • 65
    • 52
    • 28
    • 15
    • 14
    • 14
    • 12
    • 12
    • 10
    • 9
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    CSLQGRMTLT GIVSWGRGCA LKDKPGVYTR VSHFLPWIRS HTKEENGLAL
    预测反应
    Horse: 86%, Human: 100%, Rabbit: 86%, Yeast: 100%
    产品特性
    This is a rabbit polyclonal antibody against PLAU. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product PLAU Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 431 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    PLAU (Plasminogen Activator, Urokinase (PLAU))
    别名
    PLAU (PLAU 产品)
    别名
    PLAU antibody, u-PA antibody, ATF antibody, BDPLT5 antibody, QPD antibody, UPA antibody, URK antibody, uPA antibody, UPAM antibody, plasminogen activator, urokinase antibody, urokinase-type plasminogen activator antibody, PLAU antibody, CpipJ_CPIJ002131 antibody, CpipJ_CPIJ006543 antibody, CpipJ_CPIJ013396 antibody, CpipJ_CPIJ013623 antibody, Plau antibody
    背景
    This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor.
    Alias Symbols: ATF, UPA, URK, u-PA, QPD, BDPLT5
    Protein Interaction Partner: TEX101, UBC, PLAUR, SUMO1, NEDD8, CEBPG, ELAVL1, MYC, BTK, ALAS1, SCAMP5, PDGFC, ST14, SERPINA5, LRP2, SERPINF2, F2, SERPINB2, PLAT, SERPINE1, PLG, SERPINB6, IGF2R, HGF, NID1, CTSL, CTSB, MAP2K1, HRAS, SERPINE2,
    Protein Size: 431
    分子量
    28 kDa
    基因ID
    5328
    NCBI登录号
    NM_002658, NP_002649
    UniProt
    P00749
    途径
    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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