TNFRSF13C 抗体 (C-Term)
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Quick Overview for TNFRSF13C 抗体 (C-Term) (ABIN2789570)
抗原
See all TNFRSF13C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PGISDATAPA WPPPGEDPGT TPPGHSVPVP ATELGSTELV TTKTAGPEQQ
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预测反应
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against TNFRSF13C. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 184 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TNFRSF13C (Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
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别名
- TNFRSF13C
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背景
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B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Alias Symbols: BAFF-R, BAFFR, CD268, MGC138235, CVID4, BROMIX, prolixin
Protein Interaction Partner: TNFSF13B, TRAF3IP2, TRAF3, TRAF2, TRAF1, TNFRSF13C,
Protein Size: 184 -
分子量
- 20 kDa
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基因ID
- 115650
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NCBI登录号
- NM_052945, NP_443177
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UniProt
- Q96RJ3
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途径
- NF-kappaB Signaling
抗原
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