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Sclerostin 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects Sclerostin in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, 兔, 犬, Pig, 马, Cow 和 豚鼠.
产品编号 ABIN2789538
发货至: 中国
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Quick Overview for Sclerostin 抗体 (N-Term) (ABIN2789538)

抗原

See all Sclerostin (SOST) 抗体
Sclerostin (SOST)

适用

人, 小鼠, 大鼠, 兔, 犬, Pig, 马, Cow, 豚鼠

宿主

  • 65
  • 4
  • 2
  • 2
  • 1
  • 1

克隆类型

  • 66
  • 9
多克隆

标记

  • 32
  • 6
  • 6
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This Sclerostin antibody is un-conjugated

应用范围

  • 69
  • 33
  • 25
  • 24
  • 13
  • 11
  • 6
  • 5
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 9
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    PELGEYPEPP PELENNKTMN RAENGGRPPH HPFETKDVSE YSCRELHFTR

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against SOST. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 213 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Sclerostin (SOST)

    别名

    SOST

    背景

    Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
    Alias Symbols: VBCH
    Protein Interaction Partner: LRP6, LRP5,
    Protein Size: 213

    分子量

    23 kDa

    基因ID

    50964

    NCBI登录号

    NM_025237, NP_079513

    UniProt

    Q9BQB4
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