SPHK1 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for SPHK1 抗体 (Middle Region) (ABIN2789510)
抗原
See all SPHK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- SPHK1 Antibody - middle region
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序列
- DVDLESEKYR RLGEMRFTLG TFLRLAALRT YRGRLAYLPV GRVGSKTPAS
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预测反应
- Cow: 93%, Dog: 93%, Goat: 77%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against SPHK1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63467-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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别名
- SPHK1
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背景
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Background Information: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Name: Sphingosine kinase 1
Alternative Symbols: SPHK
Protein Name: Sphingosine kinase 1
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分子量
- 42kDa
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基因ID
- 8877
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NCBI登录号
- NP_001136073
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UniProt
- Q9NYA1
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途径
- VEGF Signaling
抗原
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