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MME 抗体 (C-Term)

MME 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789467
发货至: 中国
  • 抗原 See all MME 抗体
    MME (Membrane Metallo-Endopeptidase (MME))
    抗原表位
    • 16
    • 13
    • 10
    • 8
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    C-Term
    适用
    • 205
    • 57
    • 49
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    人, 小鼠, 大鼠, Pig, Cow, 犬, 马, 兔, 豚鼠
    宿主
    • 109
    • 102
    • 2
    克隆类型
    • 108
    • 104
    • 2
    多克隆
    标记
    • 106
    • 19
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    • 9
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    This MME antibody is un-conjugated
    应用范围
    • 130
    • 97
    • 78
    • 67
    • 35
    • 28
    • 22
    • 20
    • 13
    • 13
    • 10
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    Western Blotting (WB)
    序列
    EYAVNSIKTD VHSPGNFRII GTLQNSAEFS EAFHCRKNSY MNPEKKCRVW
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against MME. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product MME Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 750 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MME (Membrane Metallo-Endopeptidase (MME))
    别名
    MME (MME 产品)
    别名
    CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody
    物质类
    Chemical
    背景
    This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts.
    Alias Symbols: CALLA, CD10, DKFZp686O16152, MGC126681, MGC126707, NEP, SFE
    Protein Interaction Partner: MME, NPPA, AGT, HDAC8, UBC, NDRG1, FAM83F, RGPD6, POTEI, TUBB8, UBAC2, KBTBD3, MTDH, ITFG3, ARMC10, FAHD1, CDK5RAP3, MRPL44, NUCKS1, MRPS25, LAMTOR1, DNAJB12, SDF4, METTL7A, NNT, CPSF6, PDIA5, RUVBL2, TM9SF1, MRVI1, CLEC4M, ZMPSTE24, RBM39, ATP5J2, SLC9A3
    Protein Size: 750
    分子量
    83 kDa
    基因ID
    4311
    NCBI登录号
    NM_007287, NP_009218
    UniProt
    P08473
    途径
    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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