MME 抗体 (C-Term)
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- 抗原 See all MME 抗体
- MME (Membrane Metallo-Endopeptidase (MME))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Pig, Cow, 犬, 马, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MME antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EYAVNSIKTD VHSPGNFRII GTLQNSAEFS EAFHCRKNSY MNPEKKCRVW
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against MME. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product MME Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 750 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- MME (Membrane Metallo-Endopeptidase (MME))
- 别名
- MME (MME 产品)
- 别名
- CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody
- 物质类
- Chemical
- 背景
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This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts.
Alias Symbols: CALLA, CD10, DKFZp686O16152, MGC126681, MGC126707, NEP, SFE
Protein Interaction Partner: MME, NPPA, AGT, HDAC8, UBC, NDRG1, FAM83F, RGPD6, POTEI, TUBB8, UBAC2, KBTBD3, MTDH, ITFG3, ARMC10, FAHD1, CDK5RAP3, MRPL44, NUCKS1, MRPS25, LAMTOR1, DNAJB12, SDF4, METTL7A, NNT, CPSF6, PDIA5, RUVBL2, TM9SF1, MRVI1, CLEC4M, ZMPSTE24, RBM39, ATP5J2, SLC9A3
Protein Size: 750 - 分子量
- 83 kDa
- 基因ID
- 4311
- NCBI登录号
- NM_007287, NP_009218
- UniProt
- P08473
- 途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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