PLAUR 抗体 (N-Term)
Quick Overview for PLAUR 抗体 (N-Term) (ABIN2789360)
抗原
See all PLAUR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ELELVEKSCT HSEKTNRTLS YRTGLKITSL TEVVCGLDLC NQGNSGRAVT
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预测反应
- Human: 100%, Mouse: 82%
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产品特性
- This is a rabbit polyclonal antibody against PLAUR. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of PLAUR
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 335 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
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别名
- PLAUR
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背景
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This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Alias Symbols: CD87, UPAR, URKR
Protein Interaction Partner: TEX101, PLAU, LYN, ELAVL1, VMA21, TXNDC17, SCAF4, SDHAF2, UBQLN2, WDHD1, SELENBP1, TBCA, PSAP, CTSA, OXCT1, NOTCH2, HDLBP, CTTN, LRP1B, SURF2, SRPX2, MMP12, IL6ST, FAP, KNG1, VTN, TYK2, PFN2, JAK1, HCK, FYN, ITGB1, EEF1A1, ITGAM, LRP1, IGF2R, ITGB2, PDGFR
Protein Size: 335 -
分子量
- 37 kDa
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基因ID
- 5329
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NCBI登录号
- NM_002659, NP_002650
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UniProt
- Q9GK80
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途径
- Inositol Metabolic Process
抗原
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