BMP4 抗体 (C-Term)
Quick Overview for BMP4 抗体 (C-Term) (ABIN2789354)
抗原
See all BMP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- NWAQLRPLLV TFGHDGRGHA LTRRRRAKRS PKHHSQRARK KNKNCRRHSL
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against BMP4. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 408 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Vitreous modulation of gene expression in low-passage human retinal pigment epithelial cells." in: Investigative ophthalmology & visual science, Vol. 48, Issue 4, pp. 1853-63, (2007) (PubMed).
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: "Vitreous modulation of gene expression in low-passage human retinal pigment epithelial cells." in: Investigative ophthalmology & visual science, Vol. 48, Issue 4, pp. 1853-63, (2007) (PubMed).
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- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
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别名
- BMP4
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背景
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The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Alias Symbols: BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
Protein Interaction Partner: BMPR2, ZFYVE9, UBC, BGN, GREM2, BMPER, SOSTDC1, CHRDL2, STAP2, BMPR1B, NOG, BMP8B, HTRA1, BMPR1A, CHRDL1, BMP4, TWSG1, CHRD,
Protein Size: 408 -
分子量
- 46 kDa
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基因ID
- 652
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NCBI登录号
- NM_001202, NP_001193
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UniProt
- P12644
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途径
- Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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