HLA-C 抗体 (C-Term)
Quick Overview for HLA-C 抗体 (C-Term) (ABIN2789353)
抗原
See all HLA-C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PPKTHVTHHP LSDHEATLRC WALGFYPAEI TLTWQRDGED QTQDTELVET
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预测反应
- Human: 100%, Pig: 100%, Rabbit: 100%
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产品特性
- This is a rabbit polyclonal antibody against HLA-C. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 25-308) antibody
HLA-C 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 62-306) antibodyHLA-C 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 38-62), (C-Term) antibodyHLA-C 适用: 人 WB, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 200-306) antibodyHLA-C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 1-366) antibodyHLA-C 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) antibodyHLA-C 适用: 人, Non-Human Primate FACS, IP 宿主: 小鼠 Monoclonal DT-9 unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) antibody (PE)HLA-C 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal DT-9 PE
anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 25-308) antibody (Biotin)HLA-C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal Biotin
anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 1-366) antibodyHLA-C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 208-257) antibodyHLA-C 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 366 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HLA-C (Major Histocompatibility Complex Class I C (HLA-C))
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别名
- HLA-C
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背景
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HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described.
Alias Symbols: D6S204, FLJ27082, HLA-Cw, HLA-Cw12, HLA-JY3, HLC-C, PSORS1
Protein Interaction Partner: UBC, RNF139, NEDD8, SUMO1, ADRB2, MMS19, YBX1, CDC25A, BATF2, PRRG4, env, TANK, FBXO6, PCK1, CXCR4, KIR2DL2, KIR2DL1, LILRB2, KIR2DL3, TAPBP, LILRB1, KIR2DS4, KIR2DS2, KIR2DS1, CD8A, TAP2, HSPA5, B2M, CALR, HLA-C,
Protein Size: 366 -
分子量
- 38 kDa
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基因ID
- 3107
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NCBI登录号
- NM_002117, NP_002108
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UniProt
- Q29960
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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