Poliovirus Receptor 抗体 (N-Term)
Quick Overview for Poliovirus Receptor 抗体 (N-Term) (ABIN2789343)
抗原
See all Poliovirus Receptor (PVR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- FHQTQGPSYS ESKRLEFVAA RLGAELRNAS LRMFGLRVED EGNYTCLFVT
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against PVR. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 417 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Poliovirus Receptor (PVR)
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别名
- PVR
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背景
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The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD155, FLJ25946, HVED, NECL5, Necl-5, PVS, TAGE4
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, SLC30A2, TIGIT, TNFRSF12A, WNK1, PLA2G3, UBC, ZC3HAV1, ELAVL1, CD226, PVRL3, PVRL1, CD96, AP1M2, DYNLT3, VTN, PVR, DYNLT1,
Protein Size: 417 -
分子量
- 45 kDa
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基因ID
- 5817
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NCBI登录号
- NM_006505, NP_006496
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UniProt
- P15151
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
抗原
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