DCTN3 抗体 (C-Term)
Quick Overview for DCTN3 抗体 (C-Term) (ABIN2789148)
抗原
See all DCTN3 (Dctn3) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- ARLQRLAQIH IQQQDQCVEI TEESKALLEE YNKTTMLLSK QFVQWDELLC
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
-
产品特性
- This is a rabbit polyclonal antibody against DCTN3. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 186 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))
-
别名
- DCTN3
-
背景
-
This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants.
Alias Symbols: DCTN-22, DCTN22, MGC111190
Protein Interaction Partner: LMNB1, FLNB, FHL2, LEO1, TNKS1BP1, NUP85, CCAR2, ACTR10, DCTN2, ACTR1A, UBC, ACTR1B, DYNLT3, ATXN1, GSK3B, Dctn3, Dctn1, Capza1, PBX2,
Protein Size: 186 -
分子量
- 20 kDa
-
基因ID
- 11258
-
NCBI登录号
- NM_001248, NP_001239
-
UniProt
- O75355
-
途径
- M Phase
抗原
-